Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 7/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812598 | 0.86 | KCNMA1 (0.51) | MEN1KMT2ATMPRSS4SMN1; SMN2KCNMA1 | |
| SCHEMBL13812730 | 0.84 | TMPRSS4 (0.49) | MEN1KMT2ATMPRSS4KCNMA1ALOX15 | |
| SCHEMBL13812627 | 0.84 | MEN1 (0.55) | MEN1KMT2ATMPRSS4SMN1; SMN2KCNMA1 | |
| SCHEMBL13812592 | 0.84 | TMPRSS4 (0.55) | MEN1KMT2ATMPRSS4ALOX15P2RX1 | |
| SCHEMBL13812704 | 0.83 | MEN1 (0.49) | MEN1KMT2ATMPRSS4SMN1; SMN2KCNMA1 | |
| SCHEMBL3861646 | 0.82 | KCNMA1 (0.56) | MEN1KMT2ATMPRSS4SMN1; SMN2KCNMA1 | |
| SCHEMBL13812700 | 0.82 | KCNMA1 (0.58) | MEN1KMT2ATMPRSS4SMN1; SMN2KCNMA1 | |
| SCHEMBL13812701 | 0.82 | KCNMA1 (0.53) | MEN1KMT2ATMPRSS4KCNMA1ALOX15 | |
| SCHEMBL3863657 | 0.80 | P2RX1 (0.62) | MEN1KMT2ATMPRSS4P2RX1P2RX4 | |
| SCHEMBL13812587 | 0.80 | MAPT (0.56) | MEN1KMT2ATMPRSS4SMN1; SMN2KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |