Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 9/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.52 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812686 | 0.91 | TMPRSS4 (0.59) | KCNMA1P2RX1TMPRSS4MEN1KMT2A | |
| SCHEMBL13812625 | 0.86 | KCNMA1 (0.56) | KCNMA1P2RX1TMPRSS4MAPTMEN1 | |
| SCHEMBL13812623 | 0.84 | KCNMA1 (0.55) | KCNMA1P2RX1TMPRSS4MAPTMEN1 | |
| SCHEMBL13812624 | 0.83 | KCNMA1 (0.53) | KCNMA1P2RX1TMPRSS4MAPTMEN1 | |
| SCHEMBL13812635 | 0.83 | KCNMA1 (0.59) | KCNMA1P2RX1TMPRSS4MAPTMEN1 | |
| SCHEMBL3861646 | 0.81 | KCNMA1 (0.56) | KCNMA1P2RX1TMPRSS4MAPTMEN1 | |
| SCHEMBL13812700 | 0.81 | KCNMA1 (0.58) | KCNMA1P2RX1TMPRSS4MAPTMEN1 | |
| SCHEMBL13812648 | 0.81 | P2RX1 (0.57) | KCNMA1P2RX1TMPRSS4MAPTMEN1 | |
| SCHEMBL13812656 | 0.81 | KCNMA1 (0.55) | KCNMA1P2RX1TMPRSS4MAPTMEN1 | |
| SCHEMBL13812608 | 0.81 | P2RX1 (0.58) | KCNMA1P2RX1TMPRSS4MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |