Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 11/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | CHUK | O15111 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | MYLK | Q15746 | 1/20 | 0.47 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812628 | 0.91 | KCNMA1 (0.53) | TMPRSS4KDM4EALDH1A1P2RX1HTT | |
| SCHEMBL13812538 | 0.86 | TMPRSS4 (0.64) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 | |
| SCHEMBL13812711 | 0.86 | TMPRSS4 (0.64) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 | |
| SCHEMBL13812649 | 0.84 | TMPRSS4 (0.62) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 | |
| SCHEMBL13812832 | 0.84 | TMPRSS4 (0.62) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 | |
| SCHEMBL13812850 | 0.84 | TMPRSS4 (0.67) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 | |
| SCHEMBL13812705 | 0.83 | TMPRSS4 (0.61) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 | |
| SCHEMBL13812829 | 0.83 | TMPRSS4 (0.61) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 | |
| SCHEMBL13812886 | 0.83 | TMPRSS4 (0.63) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 | |
| SCHEMBL13812889 | 0.83 | TMPRSS4 (0.65) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |