Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812828 | 0.90 | TMPRSS4 (0.60) | KCNMA1MEN1KMT2ATMPRSS4KDM4E | |
| SCHEMBL13812653 | 0.89 | KCNMA1 (0.55) | KCNMA1MEN1USP2TP53GAA | |
| SCHEMBL13812623 | 0.89 | KCNMA1 (0.55) | KCNMA1MEN1USP2TP53GAA | |
| SCHEMBL13812684 | 0.89 | KCNMA1 (0.59) | KCNMA1MEN1USP2TP53GAA | |
| SCHEMBL13812629 | 0.87 | TMPRSS4 (0.55) | KCNMA1MEN1USP2TP53GAA | |
| SCHEMBL13812892 | 0.87 | KCNMA1 (0.51) | KCNMA1MEN1USP2TP53GAA | |
| SCHEMBL3861646 | 0.87 | KCNMA1 (0.56) | KCNMA1MEN1USP2TP53GAA | |
| SCHEMBL13812635 | 0.84 | KCNMA1 (0.59) | KCNMA1MEN1USP2TP53GAA | |
| SCHEMBL13812622 | 0.83 | KCNMA1 (0.55) | KCNMA1MEN1USP2TP53GAA | |
| SCHEMBL13812656 | 0.83 | KCNMA1 (0.55) | KCNMA1MEN1USP2TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |