Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812654 | 0.89 | KCNMA1 (0.54) | KCNMA1TAS1R3TAS1R1TAS1R2MAPT | |
| SCHEMBL13812623 | 0.88 | KCNMA1 (0.55) | KCNMA1LMNANPSR1MAPTMEN1 | |
| SCHEMBL13812629 | 0.87 | TMPRSS4 (0.55) | KCNMA1MAPTMEN1USP2TP53 | |
| SCHEMBL13812684 | 0.87 | KCNMA1 (0.59) | KCNMA1LMNAMAPTMEN1USP2 | |
| SCHEMBL13812892 | 0.85 | KCNMA1 (0.51) | KCNMA1LMNAMAPTMEN1USP2 | |
| SCHEMBL3861646 | 0.85 | KCNMA1 (0.56) | KCNMA1LMNAL3MBTL1NPSR1TAS1R3 | |
| SCHEMBL13812648 | 0.84 | P2RX1 (0.57) | KCNMA1LMNAL3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL13812828 | 0.82 | TMPRSS4 (0.60) | KCNMA1MEN1KMT2ATMPRSS4P2RX1 | |
| SCHEMBL13812539 | 0.82 | TAS1R3 (0.53) | KCNMA1LMNAL3MBTL1NPSR1TAS1R3 | |
| SCHEMBL13812635 | 0.82 | KCNMA1 (0.59) | KCNMA1TAS1R3TAS1R1TAS1R2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |