Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MET | P08581 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.53 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812750 | 0.92 | FADS1 (0.58) | POLBMETNPC1RAB9ATP53 | |
| SCHEMBL13812739 | 0.91 | SMN1; SMN2 (0.52) | POLBMETNPC1RAB9ATP53 | |
| SCHEMBL13812775 | 0.91 | KCNK3 (0.51) | POLBNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL13812765 | 0.91 | KCNK3 (0.55) | POLBNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL13812749 | 0.88 | MET (0.60) | POLBMETNPC1RAB9AKLKB1 | |
| SCHEMBL13812742 | 0.87 | KCNK3 (0.56) | POLBNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL13812936 | 0.86 | FADS1 (0.49) | POLBMETNPC1RAB9ATP53 | |
| SCHEMBL13812809 | 0.86 | POLB (0.51) | POLBNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL13812776 | 0.85 | KCNK3 (0.51) | POLBNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL13812747 | 0.85 | SMN1; SMN2 (0.52) | POLBNPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |