Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812742 | 0.90 | KCNK3 (0.56) | KDM4EKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL13812774 | 0.87 | SIRT2 (0.57) | KDM4EKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL13812765 | 0.87 | KCNK3 (0.55) | KDM4EKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL13812950 | 0.86 | RAB9A (0.58) | KDM4EKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL13812789 | 0.86 | NR1H4 (0.61) | GAAKDM4EHTTALDH1A1MAPK1 | |
| SCHEMBL13812803 | 0.85 | TRPV1 (0.50) | GAAKDM4EKCNK3KCNK9NPC1 | |
| SCHEMBL13812938 | 0.85 | GAA (0.47) | GAAKDM4EKCNK3KCNK9HTT | |
| SCHEMBL13812770 | 0.84 | KCNK3 (0.61) | KDM4EKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL13812943 | 0.83 | KDM4E (0.47) | GAAKDM4EKCNK3KCNK9HTT | |
| SCHEMBL13812809 | 0.83 | POLB (0.51) | GAAKDM4EKCNK3KCNK9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |