Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | FADS1 | O60427 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812809 | 0.95 | POLB (0.51) | TRPV1KDM4EGAANR1H4POLB | |
| SCHEMBL13812936 | 0.95 | FADS1 (0.49) | TRPV1KDM4EGAAPOLBMEN1 | |
| SCHEMBL13812934 | 0.94 | KCNK3 (0.47) | TRPV1KDM4ENR1H4POLBMEN1 | |
| SCHEMBL13812948 | 0.94 | FADS1 (0.50) | TRPV1KDM4EGAAPOLBMEN1 | |
| SCHEMBL13812946 | 0.93 | FADS1 (0.54) | KDM4EGAAPOLBMEN1KMT2A | |
| SCHEMBL13812942 | 0.93 | POLB (0.50) | KDM4EGAAPOLBMEN1KMT2A | |
| SCHEMBL13812938 | 0.91 | GAA (0.47) | TRPV1KDM4EGAAPOLBMEN1 | |
| SCHEMBL13812944 | 0.91 | KCNK3 (0.45) | TRPV1KDM4EGAANR1H4POLB | |
| SCHEMBL13812935 | 0.91 | FADS1 (0.47) | KDM4EGAAPOLBMEN1KMT2A | |
| SCHEMBL13812949 | 0.90 | RXFP1 (0.54) | KCNK3KCNK9MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |