Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 8/20 | 0.60 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812671 | 0.85 | KCNMA1 (0.56) | KCNMA1IRAK4MEN1USP2TP53 | |
| SCHEMBL13812650 | 0.82 | KCNMA1 (0.53) | KCNMA1IRAK4MEN1USP2TP53 | |
| SCHEMBL13812646 | 0.81 | KCNMA1 (0.52) | KCNMA1IRAK4MEN1USP2TP53 | |
| SCHEMBL13812895 | 0.80 | KCNMA1 (0.58) | KCNMA1IRAK4MEN1USP2TP53 | |
| SCHEMBL13812875 | 0.80 | KCNMA1 (0.59) | KCNMA1IRAK4MEN1USP2TP53 | |
| SCHEMBL13812635 | 0.80 | KCNMA1 (0.59) | KCNMA1IRAK4MEN1USP2TP53 | |
| SCHEMBL13812625 | 0.78 | KCNMA1 (0.56) | KCNMA1MEN1USP2TP53GAA | |
| SCHEMBL13812905 | 0.78 | KCNMA1 (0.57) | KCNMA1MEN1USP2TP53GAA | |
| SCHEMBL4209810 | 0.78 | TMPRSS4 (0.59) | KCNMA1MEN1KMT2AP2RX1KDM4E | |
| SCHEMBL3861646 | 0.78 | KCNMA1 (0.56) | KCNMA1MEN1USP2TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |