Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 11/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | CHUK | O15111 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | MYLK | Q15746 | 1/20 | 0.47 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812987 | 0.96 | TMPRSS4 (0.56) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812857 | 0.82 | TMPRSS4 (0.71) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812884 | 0.82 | TMPRSS4 (0.62) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812889 | 0.81 | TMPRSS4 (0.65) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL1705465 | 0.80 | TMPRSS4 (0.74) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812538 | 0.80 | TMPRSS4 (0.64) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812850 | 0.80 | TMPRSS4 (0.67) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812886 | 0.79 | TMPRSS4 (0.63) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812887 | 0.79 | TMPRSS4 (0.62) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812928 | 0.79 | TMPRSS4 (0.62) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048346-A1 | THERAPEUTIC FORMULATIONS | MYRIAD GENETICS, INCORPORATED (US) | 2009-02-19 | — | — | US | claimed |
| EP-1817019-A1 | THERAPEUTIC FORMULATIONS | MYRIAD GENETICS, INC. (US) | 2007-08-15 | — | — | EP | claimed |
| WO-2006060580-A1 | THERAPEUTIC FORMULATIONS | MYRIAD GENETICS, INC. (US) | 2006-06-08 | — | — | WO | claimed |
| US-8796267-B2 | Oxazolidinone derivatives and methods of use | CONCERT PHARMACEUTICALS, INC. (US) | 2014-08-05 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-20090048346-A1 | THERAPEUTIC FORMULATIONS | MYRIAD GENETICS, INCORPORATED (US) | 2009-02-19 | — | — | US | disclosed |
| EP-1817019-A1 | THERAPEUTIC FORMULATIONS | MYRIAD GENETICS, INC. (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006060580-A1 | THERAPEUTIC FORMULATIONS | MYRIAD GENETICS, INC. (US) | 2006-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048346-A1 | THERAPEUTIC FORMULATIONS | BAX, MCL1, ACIN1 | TMPRSS4 1273/4885P2RX1 4653/4885P2RX4 4764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.