Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 7/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.47 |
| ▸ | KDR | P35968 | 7/20 | 0.46 |
| ▸ | TEK | Q02763 | 5/20 | 0.46 |
| ▸ | LCK | P06239 | 4/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | FES | P07332 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | FGR | P09769 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | CSK | P41240 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812909 | 0.91 | TMPRSS4 (0.58) | TMPRSS4P2RX1P2RX4P2RX7KDR | |
| SCHEMBL330021 | 0.84 | TMPRSS4 (0.69) | TMPRSS4P2RX1P2RX4P2RX7KDR | |
| SCHEMBL13812897 | 0.80 | TMPRSS4 (0.65) | TMPRSS4P2RX1P2RX4P2RX7KDR | |
| SCHEMBL329953 | 0.78 | GAA (0.67) | TMPRSS4SRPK1ALDH1A1TSHRNPSR1 | |
| SCHEMBL13812851 | 0.77 | TP53 (0.63) | TMPRSS4P2RX1P2RX4P2RX7KDR | |
| SCHEMBL1705465 | 0.73 | TMPRSS4 (0.74) | TMPRSS4P2RX1P2RX4P2RX7KDR | |
| SCHEMBL330248 | 0.73 | CYP1A2 (0.61) | TMPRSS4KDRTEKLCKKMT2A | |
| SCHEMBL330166 | 0.73 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7KDR | |
| SCHEMBL330394 | 0.72 | TMPRSS4 (0.79) | TMPRSS4P2RX1P2RX4P2RX7KDR | |
| SCHEMBL330023 | 0.72 | TMPRSS4 (0.83) | TMPRSS4P2RX1P2RX4P2RX7KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |