Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.58 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | XPO1 | O14980 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 6/20 | 0.48 |
| ▸ | LCK | P06239 | 4/20 | 0.48 |
| ▸ | TEK | Q02763 | 4/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | CHUK | O15111 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | MYLK | Q15746 | 1/20 | 0.47 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.47 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.46 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.46 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812907 | 0.91 | TMPRSS4 (0.55) | TMPRSS4P2RX1P2RX4P2RX7XPO1 | |
| SCHEMBL330021 | 0.87 | TMPRSS4 (0.69) | TMPRSS4P2RX1P2RX4P2RX7XPO1 | |
| SCHEMBL13812851 | 0.81 | TP53 (0.63) | TMPRSS4P2RX1P2RX4P2RX7XPO1 | |
| SCHEMBL329953 | 0.80 | GAA (0.67) | TMPRSS4SRPK1ALDH1A1TSHRNPSR1 | |
| SCHEMBL13812897 | 0.80 | TMPRSS4 (0.65) | TMPRSS4P2RX1P2RX4P2RX7XPO1 | |
| SCHEMBL330248 | 0.75 | CYP1A2 (0.61) | TMPRSS4XPO1KDRLCKTEK | |
| SCHEMBL330166 | 0.75 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7KDR | |
| SCHEMBL330023 | 0.74 | TMPRSS4 (0.83) | TMPRSS4P2RX1P2RX4P2RX7KDR | |
| SCHEMBL18341193 | 0.73 | TMPRSS4 (0.85) | TMPRSS4P2RX1P2RX4P2RX7KDR | |
| SCHEMBL330413 | 0.73 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |