Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 10/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | MYLK | Q15746 | 1/20 | 0.45 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4209810 | 0.96 | TMPRSS4 (0.59) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 | |
| SCHEMBL13812928 | 0.84 | TMPRSS4 (0.62) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 | |
| SCHEMBL330296 | 0.81 | TMPRSS4 (0.65) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 | |
| SCHEMBL13812857 | 0.80 | TMPRSS4 (0.71) | TMPRSS4KDM4EHPGDP2RX1P2RX4 | |
| SCHEMBL13812884 | 0.80 | TMPRSS4 (0.62) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 | |
| SCHEMBL1705465 | 0.78 | TMPRSS4 (0.74) | TMPRSS4KDM4EALDH1A1P2RX1P2RX4 | |
| SCHEMBL13812902 | 0.78 | TMPRSS4 (0.59) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 | |
| SCHEMBL13812686 | 0.78 | TMPRSS4 (0.59) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 | |
| SCHEMBL13812850 | 0.78 | TMPRSS4 (0.67) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 | |
| SCHEMBL13812886 | 0.77 | TMPRSS4 (0.63) | TMPRSS4KDM4EHPGDALDH1A1P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |