Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 5/20 | 0.39 |
| ▸ | MMP9 | P14780 | 5/20 | 0.39 |
| ▸ | MMP13 | P45452 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 4/20 | 0.39 |
| ▸ | MMP7 | P09237 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12674211 | 1.00 | MMP2 (0.47) | MMP2CA12CA14PLCG1CA2 | |
| SCHEMBL14537429 | 0.85 | MMP2 (0.44) | MMP2CA12CA14PLCG1CA2 | |
| SCHEMBL12463013 | 0.82 | MMP2 (0.47) | MMP2CA12CA14PLCG1CA2 | |
| SCHEMBL881946 | 0.82 | GBA1 (0.49) | CA12CA2KMT2ACA9CA1 | |
| SCHEMBL12605150 | 0.82 | GBA1 (0.49) | CA12CA2KMT2ACA9CA1 | |
| SCHEMBL2918280 | 0.80 | ENPP2 (0.48) | CA12CA2KMT2ACA9CA1 | |
| SCHEMBL1899031 | 0.80 | TP53 (0.52) | MMP2CA2KMT2AMMP1MMP9 | |
| SCHEMBL16852254 | 0.80 | BCHE (0.46) | MMP2CA12CA2MMP9CA9 | |
| SCHEMBL9072788 | 0.80 | MAPT (0.40) | MMP2CA12CA14CA2MMP1 | |
| SCHEMBL3059582 | 0.79 | MMP2 (0.43) | MMP2CA12CA14PLCG1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090159950-A1 | Semiconductor Device and manufacturing Method of Semiconductor Device | HITACHI, LTD. | 2009-06-25 | — | — | US | disclosed |