Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 12/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.59 |
| ▸ | AURKA | O14965 | 2/20 | 0.58 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.58 |
| ▸ | PRKAA1 | Q13131 | 6/20 | 0.57 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.57 |
| ▸ | KDR | P35968 | 9/20 | 0.56 |
| ▸ | TLK2 | Q86UE8 | 3/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.56 |
| ▸ | AKT2 | P31751 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13799829 | 0.83 | AURKA (0.68) | PDGFRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8213661 | 0.78 | PDGFRB (0.75) | PDGFRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20051937 | 0.77 | ALK (0.67) | PDGFRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8210172 | 0.76 | HDAC3 (0.76) | PDGFRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8206624 | 0.76 | PDGFRB (0.75) | PDGFRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18814394 | 0.75 | ALK (0.82) | PDGFRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8199581 | 0.75 | PDGFRB (0.77) | PDGFRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8206900 | 0.75 | PDGFRB (0.77) | PDGFRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28430880 | 0.75 | KDR (0.86) | PDGFRBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28430885 | 0.75 | KDR (0.86) | PDGFRBHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163371-A1 | Anchor-Assisted Fragment Selection and Directed Assembly | ENSEMBLE THERAPEUTICS CORPORATION | 2009-06-25 | — | — | US | disclosed |