Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | JAK1 | P23458 | 3/20 | 0.36 |
| ▸ | CCR5 | P51681 | 4/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484870 | 0.95 | CYP3A4 (0.40) | CYP3A4TGFBR1ACVR1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL4111147 | 0.95 | CYP3A4 (0.39) | CYP3A4TGFBR1ACVR1DRD2DRD4 | |
| SCHEMBL13813513 | 0.94 | QPCT (0.39) | TGFBR1ACVR1DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL4110539 | 0.93 | QPCT (0.38) | TGFBR1ACVR1DRD2DRD4DRD3 | |
| SCHEMBL13800898 | 0.93 | DRD2 (0.40) | CYP3A4DRD2DRD4DRD3JAK2 | |
| SCHEMBL13800335 | 0.93 | CYP3A4 (0.39) | CYP3A4TGFBR1ACVR1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL4132310 | 0.93 | DRD2 (0.40) | CYP3A4DRD2DRD4DRD3JAK2 | |
| Hydrochloric Acid SCHEMBL7218578 | 0.92 | CYP3A4 (0.39) | CYP3A4TGFBR1ACVR1DRD2DRD4 | |
| SCHEMBL13800842 | 0.92 | CHRM2 (0.38) | CYP3A4TGFBR1ACVR1DRD2DRD4 | |
| SCHEMBL13800844 | 0.92 | CHRM2 (0.38) | CYP3A4TGFBR1ACVR1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143430-A1 | ERYTHROPOIETIN PRODUCTION ACCELERATOR | KOWA CO., LTD. (JP) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143430-A1 | ERYTHROPOIETIN PRODUCTION ACCELERATOR | EPOR, GHRHR, ARL1 | CYP3A4 3032/4885TGFBR1 2250/4885ACVR1 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.