Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1207238 | 0.91 | PTGS2 (0.41) | MAPK1KIF11CYP2C9ALDH1A1ALOX15 | |
| SCHEMBL135667 | 0.88 | MAPK1 (0.56) | MAPK1ALDH1A1ALOX15MAPTKMT2A | |
| SCHEMBL11041133 | 0.84 | PTPN1 (0.46) | MAPK1KIF11ALDH1A1ALOX15PTPN5 | |
| SCHEMBL1455249 | 0.80 | ALDH1A1 (0.41) | MAPK1ALDH1A1ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL1455251 | 0.80 | ALDH1A1 (0.41) | MAPK1ALDH1A1ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL1207241 | 0.79 | PTGS2 (0.36) | CYP2C9MAPTCYP1A2CYP1A1CYP1B1 | |
| SCHEMBL8698884 | 0.79 | KIF11 (0.41) | KIF11CYP2C9ALDH1A1PTPN5MAPT | |
| SCHEMBL138150 | 0.78 | TSHR (0.46) | MAPK1KIF11ALDH1A1ALOX15MAPT | |
| SCHEMBL10581655 | 0.75 | MAPK1 (0.50) | MAPK1KIF11CYP2C9ALDH1A1ALOX15 | |
| SCHEMBL19928040 | 0.75 | MAPK1 (0.56) | MAPK1KIF11CYP2C9ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3911 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024114776-A1 | BICYCLIC ABASIC NUCLEIC ACID ANALOGS AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | 上海舶望制药有限公司 | 2024-06-06 | — | — | WO | claimed |
| WO-2024110477-A2 | SYNTHESIS OF A CYCLIC PEPTIDE | JANSSEN PHARMACEUTICA NV (BE) | 2024-05-30 | — | — | WO | claimed |
| WO-2023167545-A1 | POLYBENZIMIDAZOLE WITH PROTECTING GROUPS, PREPARATION METHOD FOR MEMBRANE USING THE SAME AND USE THEREOF | 한국화학연구원 | 2023-09-07 | — | — | WO | claimed |
| US-20210300932-A1 | CYCLIC PEPTIDES TARGETING ALPHA-4-BETA-7 INTEGRIN | ZEALAND PHARMA A/S (DK) | 2021-09-30 | — | — | US | claimed |
| EP-3409765-B1 | KETOREDUCTASE-MEDIATED STEREOSELECTIVE ROUTE TO ALPHA CHLOROALCOHOLS | CODEXIS INC (US) | 2021-08-04 | — | — | EP | claimed |
| US-11072616-B2 | Cyclic peptides targeting alpha-4-beta-7 integrin | UNIVERSITE DE MONTREAL (CA) | 2021-07-27 | — | — | US | claimed |
| US-10954267-B2 | Dipeptide comprising a non-proteogenic amino acid | NOVO NORDISK A/S (DK) | 2021-03-23 | — | — | US | claimed |
| US-10414822-B2 | Cytotoxic and anti-mitotic compounds, and methods of using the same | ZYMEWORKS INC. (CA) | 2019-09-17 | — | — | US | claimed |
| US-20190002496-A1 | Dipeptide Comprising a Non-Proteogenic Amino Acid | NOVO NORDISK AS (DK) | 2019-01-03 | — | — | US | claimed |
| EP-2446025-B1 | KETOREDUCTASE-MEDIATED STEREOSELECTIVE ROUTE TO ALPHA CHLOROALCOHOLS | CODEXIS INC (US) | 2018-08-08 | — | — | EP | claimed |
| US-5679797-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-10-21 | — | — | US | claimed |
| US-5541206-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS INFECTION | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | claimed |
| US-5530124-A | Method for preparing cyclic ureas and their use for the synthesis of HIV protease inhibitors | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-06-25 | — | — | US | claimed |
| US-5011940-A | Process for the preparation of bicyclic amino carboxylic acids, intermediates in this process, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | claimed |
| US-4857520-A | Fused azepinone and azocinone derivatives, processes for their preparation, agents containing them and their use, and intermediates in their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-15 | — | — | US | claimed |
| US-4855486-A | Blocked, marked amino acids | KALBAG SURESH M (US) | 1989-08-08 | — | — | US | claimed |
| EP-0292228-A2 | Protecting groups for asparagine and glutamine in peptide synthesis | MILLIPORE CORPORATION (US) | 1988-11-23 | — | — | EP | claimed |
| US-4755558-A | Using internal marker | BECKMAN INSTRUMENTS, INC. (US) | 1988-07-05 | — | — | US | claimed |
| US-4012345-A | POLYPEPTIDES WHICH INHIBIT SECRETION OF GROWTH HORMONE SOMATOTROPIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-03-15 | — | — | US | claimed |
| US-3997517-A | PEPTIDE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-12-14 | — | — | US | claimed |