Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENO1 | P06733 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13607362 | 0.86 | ENO1 (0.60) | ENO1HDAC1HDAC6 | |
| SCHEMBL23346105 | 0.86 | GBA1 (0.46) | ENO1EPHX2 | |
| SCHEMBL14930846 | 0.83 | ENO1 (0.76) | ENO1HRH3 | |
| SCHEMBL23386772 | 0.82 | ENO1 (0.55) | ENO1HDAC1HDAC6 | |
| SCHEMBL13607364 | 0.82 | ENO1 (0.55) | ENO1HDAC1HDAC6 | |
| SCHEMBL18404698 | 0.77 | ENO1 (0.67) | ENO1 | |
| SCHEMBL18404766 | 0.77 | ENO1 (0.67) | ENO1 | |
| SCHEMBL14930852 | 0.74 | ENO1 (1.00) | ENO1 | |
| SCHEMBL25895682 | 0.73 | CAMK2D (0.43) | HDAC1EPHX2 | |
| SCHEMBL13607369 | 0.73 | ENO1 (0.61) | ENO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090162878-A1 | METHODS AND COMPOSITIONS FOR DETECTING AND QUANTIFYING SAPPB | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2009-06-25 | — | — | US | disclosed |