Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11611192 | 0.83 | LMNA (0.40) | LMNACYP2D6PPARGPPARATRPA1 | |
| SCHEMBL19601184 | 0.81 | LMNA (0.33) | LMNACYP2D6GRIN1GRIN2AGRIN2D | |
| SCHEMBL11663267 | 0.78 | LMNA (0.45) | LMNACYP2D6TSHRPPARGTRPA1 | |
| SCHEMBL6378216 | 0.74 | PPARG (0.39) | LMNATSHRPPARGPPARA | |
| SCHEMBL27589480 | 0.73 | LMNA (0.38) | LMNACYP2D6PPARGPPARACHRNB2 | |
| SCHEMBL17877182 | 0.73 | MAPK1 (0.41) | LMNACYP2D6TSHRPPARGRIPK1 | |
| SCHEMBL11516559 | 0.72 | LMNA (0.36) | LMNACYP2D6TSHRPPARGPPARA | |
| SCHEMBL17746055 | 0.70 | PPARG (0.49) | CYP2D6PPARGPPARAATML3MBTL1 | |
| SCHEMBL11616008 | 0.70 | LMNA (0.35) | LMNACYP2D6PPARGPPARARIPK1 | |
| SCHEMBL5286690 | 0.69 | TAAR1 (0.40) | TSHRPPARGPPARACHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065708-A1 | Method for measuring high-density lipoprotein cholesterol | Fujifilm Corporation (JP) | 2009-06-03 | — | — | EP | disclosed |