Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183720 | 0.82 | LTA4H (0.40) | TAAR1SLC6A2LTA4HCA4RIPK1 | |
| SCHEMBL5323612 | 0.80 | LTA4H (0.39) | TAAR1SLC6A2LTA4HCA4RIPK1 | |
| SCHEMBL12969444 | 0.77 | KMT2A (0.51) | ALDH1A1TSHR | |
| SCHEMBL1453725 | 0.77 | LTA4H (0.40) | LTA4HCA4RIPK1PPARGNPSR1 | |
| SCHEMBL3081094 | 0.77 | LTA4H (0.40) | LTA4HCA4RIPK1PPARGNPSR1 | |
| SCHEMBL5674225 | 0.77 | LTA4H (0.36) | TAAR1SLC6A2LTA4HCA4ALDH1A1 | |
| SCHEMBL7515025 | 0.77 | CA4 (0.43) | TAAR1SLC6A2LTA4HCA4RIPK1 | |
| SCHEMBL10760660 | 0.77 | CA4 (0.43) | TAAR1SLC6A2LTA4HCA4RIPK1 | |
| SCHEMBL11713703 | 0.77 | CA4 (0.43) | TAAR1SLC6A2LTA4HCA4RIPK1 | |
| SCHEMBL5023485 | 0.76 | KIF11 (0.46) | TAAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756107-A2 | ARYL-SUBSTITUTED PIPERAZINE DERIVATIVES | NEUROGEN CORPORATION (US) | 2007-02-28 | — | — | EP | claimed |
| WO-2006009789-A2 | ARYL-SUBSTITUTED PIPERAZINE DERIVATIVES | NEUROGEN CORPORATION (US) | 2006-01-26 | — | — | WO | claimed |
| CN-113950245-A | Herbicidal composition | 石原产业株式会社 | 2022-01-18 | — | — | CN | disclosed |
| CN-113873887-A | Herbicidal composition | 石原产业株式会社 | 2021-12-31 | — | — | CN | disclosed |