Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.69 |
| ▸ | DRD3 | P35462 | 4/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD5 | P21918 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2782101 | 0.89 | DRD2 (0.57) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL2782570 | 0.89 | DRD2 (0.57) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL2782202 | 0.88 | DRD2 (0.56) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL2783670 | 0.85 | DRD2 (0.53) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL19773023 | 0.82 | DRD2 (1.00) | DRD2DRD4SLC6A4MEN1KMT2A | |
| SCHEMBL10180799 | 0.78 | PTGDR2 (0.49) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL2782137 | 0.78 | HTR6 (0.48) | DRD2DRD3SLC6A4HTR6MEN1 | |
| SCHEMBL2784642 | 0.78 | DRD3 (0.46) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL27684032 | 0.78 | DRD3 (0.43) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL2783496 | 0.77 | DRD2 (0.64) | DRD2DRD3DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314126-B2 | Disubstituted phenylpiperdines/piperazines as modulators of dopamine neurotransmission | NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE (DK) | 2012-11-20 | — | — | US | claimed |