Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 19/20 | 0.65 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.65 |
| ▸ | ITGAL | P20701 | 19/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27465304 | 0.92 | ITGB2 (0.65) | ITGB2ICAM1ITGALTMEM97 | |
| SCHEMBL13817007 | 0.87 | ITGB2 (0.77) | ITGB2ICAM1ITGAL | |
| SCHEMBL14566279 | 0.87 | ITGB2 (0.62) | ITGB2ICAM1ITGAL | |
| SCHEMBL13817023 | 0.86 | ITGB2 (0.76) | ITGB2ICAM1ITGALTMEM97 | |
| SCHEMBL27465168 | 0.85 | ITGB2 (0.66) | ITGB2ICAM1ITGALTMEM97 | |
| SCHEMBL27465156 | 0.85 | ITGB2 (0.65) | ITGB2ICAM1ITGALTMEM97 | |
| SCHEMBL13817021 | 0.84 | ITGB2 (0.78) | ITGB2ICAM1ITGAL | |
| SCHEMBL4020169 | 0.84 | ITGB2 (0.66) | ITGB2ICAM1ITGAL | |
| SCHEMBL4020179 | 0.84 | ITGB2 (0.66) | ITGB2ICAM1ITGAL | |
| SCHEMBL2390808 | 0.84 | ITGAL (0.66) | ITGB2ICAM1ITGALTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550494-B2 | Small molecules useful in the treatment of inflammatory disease | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |