Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13236240 | 0.86 | PTGDR2 (0.47) | PTGDR2SMN1; SMN2MAPTHPGDNPC1 | |
| SCHEMBL13236218 | 0.77 | ALDH1A1 (0.37) | NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL2939746 | 0.77 | KDM4E (0.56) | PTGDR2MEN1KMT2A | |
| SCHEMBL13264602 | 0.75 | EGFR (0.34) | NPC1ALDH1A1RAB9A | |
| SCHEMBL13236238 | 0.74 | MAPT (0.39) | PTGDR2LMNAMAPTCYP2C19ALDH1A1 | |
| SCHEMBL13236205 | 0.63 | NPSR1 (0.37) | SMN1; SMN2ALKHPGDNPC1ALDH1A1 | |
| SCHEMBL12415747 | 0.63 | TLR7 (0.34) | ALKKMT2A | |
| SCHEMBL13264544 | 0.62 | L3MBTL1 (0.32) | ALKNPC1ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL13236209 | 0.62 | PTGDR2 (0.47) | PTGDR2SMN1; SMN2MCHR1LMNAMAPT | |
| SCHEMBL2950642 | 0.62 | PTGDR2 (0.44) | PTGDR2CYP1A2CYP2C19ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718649-B1 | IMIDAZO 1,2-C PYRIMIDINYLACETIC ACID DERIVATIVES | ACTIMIS PHARMACEUTICALS INC (US) | 2009-06-10 | — | — | EP | disclosed |