Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13236238 | 0.88 | MAPT (0.39) | MAPTPOLBRAB9AKMT2APTGDR2 | |
| SCHEMBL2950642 | 0.83 | PTGDR2 (0.44) | POLBKMT2APTGDR2CYP2C19NOS1 | |
| SCHEMBL5959155 | 0.76 | POLB (0.39) | MAPTPOLBRAB9ANPSR1KMT2A | |
| SCHEMBL1923032 | 0.72 | PTGDR2 (0.39) | MAPTPOLBNPSR1KMT2APTGDR2 | |
| SCHEMBL12415767 | 0.71 | ENPP1 (0.38) | MAPTPOLBRAB9AKMT2APTGDR2 | |
| SCHEMBL2944286 | 0.67 | PTGDR2 (0.48) | MAPTPOLBRAB9ANPC1KMT2A | |
| SCHEMBL1646112 | 0.64 | POLB (0.50) | MAPTPOLBRAB9AKMT2ANOS1 | |
| SCHEMBL19468191 | 0.61 | POLB (0.47) | MAPTPOLBRAB9ANPC1KMT2A | |
| SCHEMBL13236237 | 0.61 | PTGS2 (0.43) | MAPTPOLBNPSR1KMT2ACYP2C19 | |
| SCHEMBL13236234 | 0.61 | PTGS2 (0.43) | MAPTPOLBRAB9AKMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718649-B1 | IMIDAZO 1,2-C PYRIMIDINYLACETIC ACID DERIVATIVES | ACTIMIS PHARMACEUTICALS INC (US) | 2009-06-10 | — | — | EP | disclosed |