Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13236234 | 0.89 | PTGS2 (0.43) | PTGS2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL2950073 | 0.86 | CYP1A2 (0.44) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL691743 | 0.85 | KMT2A (0.41) | PTGS2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL13236241 | 0.81 | ALDH1A1 (0.39) | PTGS2MAPTALDH1A1KMT2ACYP2C19 | |
| SCHEMBL13264579 | 0.81 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2NPSR1LMNAGAA | |
| SCHEMBL12569062 | 0.81 | NPSR1 (0.41) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL27674637 | 0.79 | MAPT (0.40) | MAPTKMT2AHTTCYP2C19CYP1A2 | |
| SCHEMBL12568714 | 0.78 | TBXA2R (0.39) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL13051455 | 0.78 | L3MBTL1 (0.46) | PTGS2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL5959150 | 0.78 | MAOB (0.40) | MAPTKMT2AMEN1CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101874023-A | Alkylthio pyrimidines as CRTH2 antagonists | ACTIMIS PHARMACEUTICALS INC | 2010-10-27 | — | — | CN | disclosed |
| US-7750014-B2 | Imidazo[1,2-C]pyrimidinylacetic acid derivatives | ACTIMIS PHARMACEUTICALS, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| CN-100584844-C | Imidazole [1,2-C] pyrimidyl acetic acid derivs | ACTIMIS PHARMACEUTICALS INC | 2010-01-27 | — | — | CN | disclosed |
| EP-1718649-B1 | IMIDAZO 1,2-C PYRIMIDINYLACETIC ACID DERIVATIVES | ACTIMIS PHARMACEUTICALS INC (US) | 2009-06-10 | — | — | EP | disclosed |
| US-20090012102-A1 | Imidazo[1,2-C]Pyrimidinylacetic Acid Derivatives | ACTIMIS PHARMACEUTICALS, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| CN-1938310-A | Imidazo 1,2-c pyrimidinylacetic acid derivatives | ACTIMIS PHARMACEUTICALS INC (US) | 2007-03-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012102-A1 | Imidazo[1,2-C]Pyrimidinylacetic Acid Derivatives | HRH2, CCR2, HRH1 | PTGS2 90/4885MAPT 2950/4885RECQL 4639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.