Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8357649 | 0.77 | MAPT (0.38) | ALDH1A1MAPK1 | |
| SCHEMBL13023901 | 0.77 | MAPK1 (0.41) | L3MBTL1HTTALDH1A1IDO1MAPK1 | |
| SCHEMBL13929158 | 0.76 | HDAC4 (0.38) | HPGDL3MBTL1TYRMGLLHTT | |
| SCHEMBL19729049 | 0.76 | HPGD (0.42) | HPGDL3MBTL1TYRTNKSTNKS2 | |
| SCHEMBL29281399 | 0.75 | HPGD (0.40) | HPGDL3MBTL1TYRMGLLTNKS | |
| SCHEMBL10070523 | 0.75 | ACHE (0.40) | ALDH1A1 | |
| SCHEMBL14113928 | 0.74 | HPGD (0.41) | HPGDL3MBTL1TYRMGLLTNKS | |
| SCHEMBL13268160 | 0.74 | ACHE (0.42) | — | |
| SCHEMBL13268162 | 0.74 | DHODH (0.39) | ALDH1A1 | |
| SCHEMBL5704436 | 0.73 | CYP2A6 (0.38) | ALDH1A1IDO1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076622-A2 | LIGANDS FOR TRANSITION-METAL-CATALYZED CROSS-COUPLINGS, AND METHODS OF USE THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-06-18 | — | — | WO | disclosed |
| US-7504411-B2 | 2,3,6-Trisubstituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-03-17 | — | — | US | disclosed |