Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13818514 | 0.83 | BCL2 (0.71) | BCL2PTGS2FGFR1RXRARXRB | |
| SCHEMBL13818585 | 0.83 | ALDH1A1 (0.45) | BCL2RXRARXRB | |
| SCHEMBL13675346 | 0.81 | BCL2 (0.71) | BCL2PTGS2FGFR1RXRARXRB | |
| SCHEMBL13818693 | 0.78 | BCL2 (0.63) | BCL2PTGS2FGFR1RXRARXRB | |
| SCHEMBL12894971 | 0.78 | BCL2 (0.62) | BCL2PTGS2FGFR1IDO1PRKCI | |
| SCHEMBL13099462 | 0.77 | BCL2 (0.76) | BCL2PTGS2FGFR1RXRARXRB | |
| SCHEMBL12894973 | 0.77 | BCL2 (1.00) | BCL2PTGS2RXRARXRBAOC3 | |
| SCHEMBL16795609 | 0.77 | ALDH1A1 (0.50) | RXRARXRBIDO1 | |
| SCHEMBL9007144 | 0.77 | BCL2 (0.65) | BCL2PTGS2FGFR1IDO1PRKCI | |
| SCHEMBL10204736 | 0.77 | SMN1; SMN2 (0.45) | MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070909-A1 | Non-steroidal progesterone receptor modulators | Bayer Schering Pharma AG (DE) | 2009-06-17 | — | — | EP | disclosed |