Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.39 |
| ▸ | DHFR | P00374 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13818514 | 0.81 | BCL2 (0.71) | BCL2PTGS2RXRARXRBFGFR1 | |
| SCHEMBL13818521 | 0.78 | BCL2 (0.62) | BCL2PTGS2RXRARXRBFGFR1 | |
| SCHEMBL13099462 | 0.78 | BCL2 (0.76) | BCL2PTGS2RXRARXRBFGFR1 | |
| SCHEMBL12894973 | 0.78 | BCL2 (1.00) | BCL2PTGS2RXRARXRBAOC3 | |
| SCHEMBL6640696 | 0.76 | BCL2 (0.73) | BCL2PTGS2RXRARXRBFGFR1 | |
| SCHEMBL17740358 | 0.75 | BCL2 (0.71) | BCL2PTGS2RXRARXRBDHFR | |
| SCHEMBL13675346 | 0.75 | BCL2 (0.71) | BCL2PTGS2RXRARXRBFGFR1 | |
| SCHEMBL13814763 | 0.74 | BCL2 (0.57) | BCL2PTGS2RXRARXRBFGFR1 | |
| SCHEMBL9007144 | 0.74 | BCL2 (0.65) | BCL2PTGS2FGFR1IDO1MME | |
| SCHEMBL29924029 | 0.74 | BCL2 (0.65) | BCL2PTGS2FGFR1IDO1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070909-A1 | Non-steroidal progesterone receptor modulators | Bayer Schering Pharma AG (DE) | 2009-06-17 | — | — | EP | disclosed |