Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828473 | 0.88 | HPGD (0.67) | HPGDALDH1A1TSHRTDP1LMNA | |
| SCHEMBL13818522 | 0.84 | TP53 (0.51) | HPGDALDH1A1TDP1LMNANPC1 | |
| SCHEMBL2225313 | 0.84 | HPGD (0.77) | HPGDALDH1A1TSHRGAATDP1 | |
| SCHEMBL10722469 | 0.82 | HPGD (0.69) | HPGDALDH1A1TSHRGAATDP1 | |
| SCHEMBL5254287 | 0.81 | HPGD (0.57) | HPGDALDH1A1TSHRGAATDP1 | |
| SCHEMBL5254289 | 0.81 | HPGD (0.57) | HPGDALDH1A1TSHRGAATDP1 | |
| SCHEMBL1005865 | 0.81 | HPGD (0.82) | HPGDALDH1A1TSHRGAALMNA | |
| SCHEMBL9016911 | 0.79 | ALDH1A1 (0.55) | HPGDALDH1A1PPARG | |
| SCHEMBL16613822 | 0.79 | HPGD (0.65) | HPGDALDH1A1TSHRGAATDP1 | |
| SCHEMBL14234683 | 0.78 | HPGD (0.53) | HPGDALDH1A1TSHRGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070909-A1 | Non-steroidal progesterone receptor modulators | Bayer Schering Pharma AG (DE) | 2009-06-17 | — | — | EP | disclosed |