Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | DRD1 | P21728 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
| ▸ | DRD5 | P21918 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 5/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13818587 | 0.86 | HRH3 (0.53) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL18165028 | 0.81 | BCHE (0.46) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL6513977 | 0.81 | BCHE (0.50) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL380954 | 0.81 | CNR1 (0.50) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL13775217 | 0.81 | HRH3 (0.52) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL20462967 | 0.80 | TSHR (0.48) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL8494349 | 0.80 | ALDH1A1 (0.52) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL7493624 | 0.79 | TRPA1 (0.44) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL1206253 | 0.79 | TSHR (0.50) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL2910597 | 0.78 | TRPA1 (0.42) | DRD2DRD3DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070909-A1 | Non-steroidal progesterone receptor modulators | Bayer Schering Pharma AG (DE) | 2009-06-17 | — | — | EP | disclosed |