Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.73 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | RXRA | P19793 | 3/20 | 0.51 |
| ▸ | RXRB | P28702 | 3/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 2/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12894973 | 0.85 | BCL2 (1.00) | BCL2PTGS2RXRARXRBAOC3 | |
| SCHEMBL13099462 | 0.85 | BCL2 (0.76) | BCL2PTGS2RXRARXRBMME | |
| SCHEMBL7123177 | 0.82 | ALDH1A1 (0.57) | BCL2RXRARXRBSMN1; SMN2 | |
| SCHEMBL13675346 | 0.82 | BCL2 (0.71) | BCL2PTGS2RXRARXRBMME | |
| SCHEMBL17740358 | 0.82 | BCL2 (0.71) | BCL2PTGS2RXRARXRBDHFR | |
| SCHEMBL13060851 | 0.81 | BCL2 (0.69) | BCL2PTGS2RXRARXRBAOC3 | |
| SCHEMBL19149187 | 0.81 | BCL2 (0.69) | BCL2PTGS2RXRARXRBMME | |
| SCHEMBL3890873 | 0.80 | CNR2 (0.51) | BCL2PTGS2MAPTSMN1; SMN2 | |
| SCHEMBL13060799 | 0.80 | HPGD (0.69) | BCL2PTGS2RXRARXRBAOC3 | |
| SCHEMBL726544 | 0.78 | KMO (0.53) | BCL2RXRARXRBRXRGHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931060-A4 | SUBSTITUTED N- (AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL]PROPYL AMIDES | AVENTIS PHARMA INC (US) | 2004-10-06 | — | — | EP | disclosed |
| EP-0906094-B1 | SUBSTITUTED N- (AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL]PROPYL AMIDES | AVENTIS PHARMA INC (US) | 2003-06-25 | — | — | EP | disclosed |
| US-6323227-B1 | PRODRUGS | AVENTIS PHARMACEUTICALS PRODUCTS INC. | 2001-11-27 | — | — | US | disclosed |
| US-6140504-A | Substituted intermediate compounds for the preparation of n-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-10-31 | — | — | US | disclosed |
| US-6080767-A | Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-06-27 | — | — | US | disclosed |
| EP-0906094-A4 | SUBSTITUTED N- (AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL]PROPYL AMIDES | RHONE POULENC RORER PHARMA (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0931060-A1 | SUBSTITUTED N- (AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL]PROPYL AMIDES | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-07-28 | — | — | EP | disclosed |
| EP-0906094-A1 | SUBSTITUTED N- (AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL]PROPYL AMIDES | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-04-07 | — | — | EP | disclosed |
| WO-1999000356-A1 | SUBSTITUTED N-[(AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL]PROPYL AMIDES | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1999-01-07 | — | — | WO | disclosed |
| WO-1997024118-A1 | SUBSTITUTED N-[(AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL]PROPYL AMIDES | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1997-07-10 | — | — | WO | disclosed |