Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13522282 | 0.94 | HRH2 (0.35) | NPC1RAB9APOLBCYP2C9LMNA | |
| SCHEMBL14401995 | 0.85 | ESR1 (0.34) | NPC1RAB9APOLBCYP2C9ESR1 | |
| SCHEMBL13819209 | 0.80 | NPC1 (0.39) | NPC1RAB9APOLBCYP2C9LMNA | |
| SCHEMBL13818940 | 0.79 | RAB9A (0.46) | NPC1RAB9APOLBCYP2C9LMNA | |
| SCHEMBL13329348 | 0.77 | NPC1 (0.41) | NPC1RAB9APOLBCYP2C9LMNA | |
| SCHEMBL12463907 | 0.77 | SRD5A2 (0.35) | NPC1RAB9APOLBCYP2C9MAPT | |
| SCHEMBL13522285 | 0.77 | NPC1 (0.37) | NPC1RAB9APOLBCYP2C9LMNA | |
| SCHEMBL13520473 | 0.76 | ESR1 (0.40) | POLBLMNAESR1ESR2SRD5A2 | |
| SCHEMBL13818909 | 0.76 | NPC1 (0.43) | NPC1RAB9APOLBCYP2C9LMNA | |
| SCHEMBL14401994 | 0.73 | ESR1 (0.37) | NPC1RAB9APOLBCYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149625-A1 | AROMATIC COMPOUND HAVING FLUORENE SKELETON AND POLYARYLENE HAVING SULFONIC ACID GROUP | JSR CORPORATION (JP) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149625-A1 | AROMATIC COMPOUND HAVING FLUORENE SKELETON AND POLYARYLENE HAVING SULFONIC ACID GROUP | AFF2, FGFR1, FUS | NPC1 4055/4885RAB9A 3087/4885POLB 2522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.