Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 6/20 | 0.33 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | PPARD | Q03181 | 6/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819209 | 0.89 | NPC1 (0.39) | NPC1RAB9APOLBCYP2C9ESR1 | |
| SCHEMBL14401994 | 0.82 | ESR1 (0.37) | NPC1RAB9APOLBCYP2C9ESR1 | |
| SCHEMBL13819211 | 0.82 | NPC1 (0.39) | NPC1RAB9APOLBCYP2C9CHRM5 | |
| SCHEMBL13818909 | 0.80 | NPC1 (0.43) | NPC1RAB9APOLBCYP2C9CHRM5 | |
| SCHEMBL13522286 | 0.79 | LMNA (0.37) | NPC1RAB9ACYP2C9ESR1ESR2 | |
| SCHEMBL13818940 | 0.77 | RAB9A (0.46) | NPC1RAB9APOLBCYP2C9FGFR2 | |
| SCHEMBL13106027 | 0.77 | ESR1 (0.46) | POLBESR1ESR2CHRM5PPARA | |
| SCHEMBL13819210 | 0.77 | NPC1 (0.40) | NPC1RAB9APOLBCYP2C9ESR1 | |
| SCHEMBL13321966 | 0.75 | ESR1 (0.44) | POLBESR1ESR2CHRM5LMNA | |
| SCHEMBL4893479 | 0.75 | RXRA (0.52) | ESR1ESR2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645534-B2 | Membrane electrode assembly for solid polymer electrolyte fuel cell | HONDA MOTOR CO., LTD. (JP) | 2010-01-12 | — | — | US | disclosed |