Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.46 |
| ▸ | PPARG | P37231 | 16/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819723 | 0.87 | PPARA (0.46) | PPARAPPARGPPARD | |
| SCHEMBL13819375 | 0.84 | PPARA (0.47) | PPARAPPARGPPARD | |
| SCHEMBL4341762 | 0.81 | PPARA (0.42) | PPARAPPARGPPARDLMNA | |
| SCHEMBL4483847 | 0.81 | PPARA (0.42) | PPARAPPARGPPARD | |
| SCHEMBL13819769 | 0.79 | PPARG (0.55) | PPARAPPARGPPARDLMNA | |
| SCHEMBL13819487 | 0.78 | PPARG (0.51) | PPARAPPARGPPARD | |
| SCHEMBL13819285 | 0.78 | PPARG (0.46) | PPARAPPARGPPARD | |
| SCHEMBL4329800 | 0.78 | PPARA (0.42) | PPARAPPARGPPARD | |
| SCHEMBL13819481 | 0.77 | SHMT1 (0.51) | PPARAPPARGPPARD | |
| SCHEMBL13819776 | 0.75 | MRGPRX4 (0.59) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |