Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.50 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | F7 | P08709 | 3/20 | 0.47 |
| ▸ | F3 | P13726 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17676487 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP19A1OXER1PPARGMAPT | |
| SCHEMBL15223579 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP19A1OXER1PPARGMAPT | |
| SCHEMBL839630 | 0.92 | — | — | |
| SCHEMBL801900 | 0.92 | — | — | |
| SCHEMBL839631 | 0.92 | — | — | |
| SCHEMBL18868445 | 0.81 | ALDH1A1 (0.47) | ALDH1A1ALOX15TDP1KDM4ELMNA | |
| SCHEMBL12572575 | 0.81 | ALDH1A1 (0.47) | ALDH1A1ALOX15TDP1KDM4ELMNA | |
| SCHEMBL23803612 | 0.80 | ALDH1A1 (0.61) | ALDH1A1CYP19A1OXER1PPARGMAPT | |
| SCHEMBL7625812 | 0.80 | ALDH1A1 (0.61) | ALDH1A1CYP19A1OXER1PPARGMAPT | |
| SCHEMBL12621471 | 0.80 | ALDH1A1 (0.61) | ALDH1A1CYP19A1OXER1PPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9433577-B2 | Pharmaceutical composition comprising oligopeptides | MERCK PATENT GMBH (DE) | 2016-09-06 | — | — | US | disclosed |
| US-20160228551-A1 | Method of Treating Disorders using a Pharmaceutical Composition of Oligopeptides | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | US | disclosed |
| US-20120288539-A1 | PHARMACEUTICAL COMPOSITION COMPRISING OLIGOPEPTIDES | MERCK PATENT GMBH (DE) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120288539-A1 | PHARMACEUTICAL COMPOSITION COMPRISING OLIGOPEPTIDES | VIP, LNPEP, IAPP | ALDH1A1 4801/4885CYP19A1 2589/4885OXER1 2165/4885 |
| US-20160228551-A1 | Method of Treating Disorders using a Pharmaceutical Composition of Oligopeptides | IAPP, PCSK9, VIP | ALDH1A1 4688/4885CYP19A1 2198/4885OXER1 1789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.