Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146196 | 0.77 | CSNK1A1 (0.36) | CSNK1A1CLK4HTTPIN1LRRK2 | |
| SCHEMBL12186129 | 0.69 | S1PR1 (0.38) | CSNK1A1CLK4HTTNPC1ALDH1A1 | |
| SCHEMBL18999987 | 0.68 | LRRK2 (0.35) | CSNK1A1CLK4HTTLRRK2AR | |
| SCHEMBL24827277 | 0.67 | TLR9 (0.41) | CSNK1A1CLK4HTTPIN1LRRK2 | |
| SCHEMBL15934911 | 0.66 | ALDH1A1 (0.39) | HTTLRRK2ARKDM5ANPC1 | |
| SCHEMBL13058613 | 0.63 | CYP11B1 (0.35) | LRRK2ARKDM5ANPC1ALDH1A1 | |
| SCHEMBL20691191 | 0.63 | CSNK1A1 (0.35) | CSNK1A1CLK4HTTLRRK2AR | |
| SCHEMBL26462871 | 0.63 | HPGDS (0.39) | HTTLRRK2ARKDM5ANPC1 | |
| SCHEMBL2872592 | 0.63 | CSNK1A1 (0.35) | CSNK1A1CLK4HTTLRRK2AR | |
| SCHEMBL28187266 | 0.63 | CSNK1A1 (0.35) | CSNK1A1CLK4HTTLRRK2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076602-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | WYETH (US) | 2009-06-18 | — | — | WO | disclosed |