Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21156715 | 0.77 | NPSR1 (0.37) | NPSR1L3MBTL1CNR2POLBMAPK1 | |
| SCHEMBL152945 | 0.70 | SIGMAR1 (0.40) | NPSR1L3MBTL1CNR2POLBMAPK1 | |
| SCHEMBL20364044 | 0.70 | NPSR1 (0.39) | NPSR1L3MBTL1CNR2POLBMAPK1 | |
| SCHEMBL2321287 | 0.69 | NPSR1 (0.38) | NPSR1L3MBTL1CNR2POLBMAPK1 | |
| SCHEMBL16643942 | 0.69 | CYP2C9 (0.45) | NPSR1L3MBTL1CNR2POLBMAPK1 | |
| SCHEMBL24543187 | 0.69 | NPSR1 (0.38) | NPSR1L3MBTL1CNR2POLBMAPK1 | |
| SCHEMBL16643945 | 0.69 | CYP2C9 (0.45) | NPSR1L3MBTL1CNR2POLBMAPK1 | |
| SCHEMBL16643953 | 0.69 | CYP2C9 (0.45) | NPSR1L3MBTL1CNR2POLBMAPK1 | |
| SCHEMBL24263148 | 0.69 | CNR2 (0.37) | NPSR1L3MBTL1CNR2POLBMAPK1 | |
| SCHEMBL24263151 | 0.69 | CNR2 (0.37) | NPSR1L3MBTL1CNR2POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414797-B9 | HEPATITIS C VIRUS POLYMERASE INHIBITORS WITH A HETEROBICYLIC STRUCTURE | BOEHRINGER INGELHEIM CA LTD (CA) | 2009-04-15 | — | — | EP | disclosed |
| EP-1414797-B1 | HEPATITIS C VIRUS POLYMERASE INHIBITORS WITH A HETEROBICYLIC STRUCTURE | BOEHRINGER INGELHEIM CA LTD (CA) | 2008-01-02 | — | — | EP | disclosed |