SCHEMBL24263148

SCHEMBL24263148

CC(C)(C)C(=O)C[C@@H](F)NC(=O)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.37
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.30
POLB P06746 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24263151 1.00 CNR2 (0.37) CNR2NPSR1L3MBTL1POLBMAPK1
SCHEMBL24263116 0.77 CNR2 (0.34) CNR2NPSR1L3MBTL1POLBMAPK1
SCHEMBL24263122 0.77 CNR2 (0.34) CNR2NPSR1L3MBTL1POLBMAPK1
SCHEMBL24349877 0.74 APLNR (0.34)
SCHEMBL24349876 0.74 APLNR (0.34)
SCHEMBL24262982 0.73 CA1 (0.37) CNR2NPSR1
SCHEMBL25928849 0.73 ACE (0.36) CNR2NPSR1POLBMAPK1
SCHEMBL24263334 0.73 CA1 (0.37) CNR2NPSR1
SCHEMBL24349875 0.72 POLB (0.31) POLB
SCHEMBL24349874 0.72 POLB (0.31) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220062273-A1 CONJUGATES OF PATTERN RECOGNITION RECEPTOR AGONISTS Ascendis Pharma Oncology Division A/S (DK) 2022-03-03 US disclosed
US-20220054477-A1 INDUCTION OF SUSTAINED LOCAL INFLAMMATION Ascendis Pharma Oncology Division A/S (DK) 2022-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220054477-A1 INDUCTION OF SUSTAINED LOCAL INFLAMMATION GRPR, TLR3, TLR1 CNR2 328/4885NPSR1 37/4885L3MBTL1 4794/4885
US-20220062273-A1 CONJUGATES OF PATTERN RECOGNITION RECEPTOR AGONISTS LPAR1, TACR1, ADGRF1 CNR2 361/4885NPSR1 23/4885L3MBTL1 2200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.