Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | CFTR | P13569 | 1/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10040697 | 0.92 | ABCB1 (0.71) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL14219787 | 0.90 | ABCB1 (0.55) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL12949260 | 0.90 | ABCB1 (0.54) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL13179036 | 0.89 | ABCB1 (0.56) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL13989007 | 0.88 | MAOB (0.46) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL22851948 | 0.86 | MAOB (0.45) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL10298327 | 0.86 | USP2 (0.58) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL13820277 | 0.86 | ABCB1 (0.54) | ABCB1ATMUSP2CFTRPAX8 | |
| Hydrochloric Acid SCHEMBL23064866 | 0.86 | USP2 (0.57) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL20042562 | 0.86 | ABCB1 (0.80) | ABCB1ATMUSP2CFTRPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962339-B2 | Fluorescent probe compounds, preparation method and application thereof | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2015-02-24 | — | — | US | disclosed |
| US-8962339-B2 | Fluorescent probe compounds, preparation method and application thereof | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2015-02-24 | — | — | US | disclosed |
| US-8664406-B2 | Fluorescent probe compounds, preparation method and use thereof | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2014-03-04 | — | — | US | disclosed |
| US-8664406-B2 | Fluorescent probe compounds, preparation method and use thereof | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2014-03-04 | — | — | US | disclosed |
| US-20130137879-A1 | FLUORESCENT PROBE COMPOUNDS, PREPARATION METHOD AND USE THEREOF | DALIAN CHRPMAS BIOSCIENCE CO., LTD. (CN) | 2013-05-30 | — | — | US | disclosed |
| US-20130137879-A1 | FLUORESCENT PROBE COMPOUNDS, PREPARATION METHOD AND USE THEREOF | DALIAN CHRPMAS BIOSCIENCE CO., LTD. (CN) | 2013-05-30 | — | — | US | disclosed |
| US-20120288947-A1 | FLUORESCENT PROBE COMPOUNDS, PREPARATION METHOD AND APPLICATION THEREOF | DALIAN CHROMAS BIOSCIENCE CO., LTD (CN) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120288947-A1 | FLUORESCENT PROBE COMPOUNDS, PREPARATION METHOD AND APPLICATION THEREOF | PDCD1LG2, PDCD1, CD274 | ABCB1 494/4885ATM 2455/4885USP2 1615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.