Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.71 |
| ▸ | ATM | Q13315 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 2/20 | 0.69 |
| ▸ | CFTR | P13569 | 1/20 | 0.69 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.69 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 4/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25C | P30307 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13820288 | 0.92 | ABCB1 (0.59) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL15483871 | 0.90 | ABCB1 (0.56) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL13179036 | 0.89 | ABCB1 (0.56) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL14046505 | 0.88 | ABCB1 (0.55) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL14219787 | 0.88 | ABCB1 (0.55) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL12949260 | 0.87 | ABCB1 (0.54) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL9007850 | 0.86 | USP2 (0.59) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL15100480 | 0.86 | ABCB1 (0.53) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL20041379 | 0.85 | ABCB1 (0.71) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL14534275 | 0.85 | ABCB1 (0.54) | ABCB1ATMUSP2CFTRPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120039990-A1 | Liposome Compositions and Methods of Use Thereof | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120039990-A1 | Liposome Compositions and Methods of Use Thereof | LIPA, PHLPP1, PHLPP2 | ABCB1 2883/4885ATM 4682/4885USP2 1114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.