Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | CFTR | P13569 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.53 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.41 |
| ▸ | FPR2 | P25090 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219787 | 0.92 | ABCB1 (0.55) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL13820288 | 0.90 | ABCB1 (0.59) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL18888026 | 0.88 | USP2 (0.53) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL10040697 | 0.87 | ABCB1 (0.71) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL18888058 | 0.85 | ABCB1 (0.40) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL13179036 | 0.84 | ABCB1 (0.56) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL2732905 | 0.83 | ABCB1 (0.43) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL22292200 | 0.83 | USP2 (0.55) | ABCB1USP2ATMCFTRPAX8 | |
| Hydrochloric Acid SCHEMBL29539118 | 0.82 | USP2 (0.54) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL18350813 | 0.81 | USP2 (0.53) | ABCB1USP2ATMCFTRPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021616-A1 | HALOGENATED RHODAMINE DERIVATIVES AND APPLICATIONS THEREOF | KIADIS PHARMA CANADA INC. (CA) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021616-A1 | HALOGENATED RHODAMINE DERIVATIVES AND APPLICATIONS THEREOF | RAB7A, BCDIN3D, TFEB | ABCB1 1138/4885USP2 4534/4885ATM 3083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.