Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203104 | 0.88 | RAB9A (0.56) | KMT2ARAB9ANPC1FFAR2MEN1 | |
| SCHEMBL4203468 | 0.84 | EPHX2 (0.54) | KMT2ARAB9AHDAC6MEN1ALDH1A1 | |
| SCHEMBL13822123 | 0.83 | MAPK8 (0.49) | KMT2AMEN1ALDH1A1NLRP3MAPT | |
| SCHEMBL4211528 | 0.77 | CYP1A2 (0.57) | KMT2ARAB9ANPC1MEN1ALDH1A1 | |
| SCHEMBL3265438 | 0.77 | MEN1 (0.57) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3110192 | 0.74 | RECQL (0.54) | KMT2ARAB9ANPC1MEN1ALDH1A1 | |
| SCHEMBL4215163 | 0.73 | NPC1 (0.54) | KMT2ARAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL7931373 | 0.72 | MAPT (0.47) | KMT2AHDAC6MEN1ALDH1A1MAPT | |
| SCHEMBL4209304 | 0.72 | POLB (0.43) | KMT2ARAB9ANPC1HDAC6MEN1 | |
| SCHEMBL15449548 | 0.71 | ALDH1A1 (0.44) | KMT2ARAB9ANPC1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009078999-A1 | IMIDAZOLO-, OXAZOLO-, AND THIAZOLOPYRIMIDINE MODULATORS OF TRPV1 | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |