Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332250 | 0.79 | ADORA3 (0.66) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL20390156 | 0.77 | SMN1; SMN2 (0.43) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL13822157 | 0.77 | ADORA3 (0.49) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL20390138 | 0.76 | ADORA3 (0.66) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL9108544 | 0.76 | ADORA3 (0.66) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL16238754 | 0.76 | ADORA3 (0.66) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL20390644 | 0.76 | ADORA3 (0.66) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL9852272 | 0.76 | ADORA3 (0.66) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL13659745 | 0.75 | ADORA3 (0.59) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL9852337 | 0.75 | ADORA3 (0.59) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203435-B1 | 6, 11-BRIDGED BIARYL MACROLIDES | ENANTA PHARM INC (US) | 2018-07-18 | — | — | EP | disclosed |
| WO-2009075923-A2 | 6, 11-BRIDGED BIARYL MACROLIDES | ENANTA PHARMACEUTICALS, INC. (US) | 2009-06-18 | — | — | WO | disclosed |