Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 13/20 | 0.45 |
| ▸ | NPC1 | O15118 | 12/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.45 |
| ▸ | HPGD | P15428 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17544495 | 0.79 | PBRM1 (0.46) | PBRM1RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL30402371 | 0.79 | PBRM1 (0.46) | PBRM1RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL30402429 | 0.79 | RAB9A (0.52) | PBRM1RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL17544208 | 0.79 | RAB9A (0.52) | PBRM1RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL23458479 | 0.75 | PIK3CB (0.44) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL14973920 | 0.75 | SMN1; SMN2 (0.52) | PBRM1RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL22744419 | 0.73 | MAP4K4 (0.48) | PBRM1RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL14974195 | 0.73 | MAPT (0.45) | PBRM1RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL14693918 | 0.72 | PBRM1 (0.58) | PBRM1RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL17585007 | 0.71 | RAB9A (0.78) | PBRM1RAB9ANPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785439-B2 | 2,5,7-substituted oxazolopyrimidine derivatives | SANOFI (FR) | 2014-07-22 | — | — | US | disclosed |
| US-20130137685-A1 | 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE DERIVATIVES | SANOFI (FR) | 2013-05-30 | — | — | US | disclosed |
| EP-2523961-A1 | 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE DERIVATIVES | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137685-A1 | 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE DERIVATIVES | DPYD, UNG, CDK2 | PBRM1 2363/4885RAB9A 3663/4885NPC1 4691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.