Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GALR1 | P47211 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13822289 | 0.95 | TDP1 (0.41) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL13822599 | 0.93 | ALDH1A1 (0.42) | TDP1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL13583500 | 0.92 | ALDH1A1 (0.48) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL13583604 | 0.90 | ALDH1A1 (0.44) | ALDH1A1KDM4ETP53MEN1KMT2A | |
| SCHEMBL13822310 | 0.89 | TAS1R3 (0.44) | TDP1ALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL13583620 | 0.86 | MEN1 (0.46) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL13822294 | 0.85 | MEN1 (0.44) | TDP1MEN1KMT2AGAA | |
| SCHEMBL13822277 | 0.85 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL13583393 | 0.85 | FNTA (0.44) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL13583212 | 0.84 | KDM4E (0.43) | TDP1ALDH1A1KDM4ETP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2524686-B1 | PIGMENTATION-PREVENTING OR -AMELIORATING AGENT | POLA CHEM IND INC (JP) | 2017-06-21 | — | — | EP | disclosed |
| EP-2524686-A1 | PIGMENTATION-PREVENTING OR -AMELIORATING AGENT | Pola Chemical Industries Inc. (JP) | 2012-11-21 | — | — | EP | disclosed |