Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128091 | 0.81 | NPC1 (0.81) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL14364648 | 0.79 | NPC1 (0.54) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL12646212 | 0.78 | NPC1 (0.53) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL10066693 | 0.78 | NPC1 (0.53) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL17751402 | 0.77 | HTT (0.55) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL26717832 | 0.76 | ALDH1A1 (0.47) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL23252380 | 0.76 | ALDH1A1 (0.56) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL21534740 | 0.76 | NPC1 (0.50) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL23335972 | 0.76 | NPC1 (0.50) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL10180000 | 0.75 | ALDH1A1 (0.46) | NPC1RAB9AMAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550216-B2 | Composite solid polymer electrolyte membranes | FOSTER-MILLER, INC. (US) | 2009-06-23 | — | — | US | disclosed |