Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | DRD1 | P21728 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13823392 | 0.93 | ADRB2 (0.60) | ADRB2ADRB1ADRA1DDRD2DRD1 | |
| SCHEMBL13823394 | 0.92 | ADRB2 (0.61) | ADRB2ADRB1ADRA1DDRD2DRD1 | |
| SCHEMBL2746764 | 0.92 | ADRB2 (0.64) | ADRB2ADRB1ADRA1DDRD2DRD1 | |
| SCHEMBL13823367 | 0.91 | ADRB2 (0.65) | ADRB2ADRB1 | |
| SCHEMBL2747773 | 0.87 | ADRB2 (0.62) | ADRB2ADRB1ADRA1DDRD2DRD1 | |
| SCHEMBL2747903 | 0.86 | ADRB2 (0.64) | ADRB2ADRB1ADRA1DDRD2DRD1 | |
| SCHEMBL2747771 | 0.83 | ADRB2 (0.61) | ADRB2ADRB1ADRA1DDRD2DRD1 | |
| SCHEMBL13823217 | 0.83 | ADRB2 (0.65) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL2747808 | 0.82 | ADRB2 (0.68) | ADRB2ADRB1 | |
| SCHEMBL2747769 | 0.81 | ADRB2 (0.64) | ADRB2ADRB1ADRA1DDRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009068177-A1 | DERIVATIVES OF 4-(2-AMINO-1 -HYDROXYETHYL)PHENOL AS AGONISTS OF THE β2 ADRENERGIC RECEPTOR | ALMIRALL, S.A. (ES) | 2009-06-04 | — | — | WO | disclosed |