SCHEMBL13823367

SCHEMBL13823367

O=c1ccc2c([C@@H](O)CNCCc3ccc(OCC45CC6CC(CC4C6)C5)cc3)ccc(O)c2[nH]1

nearest known ligand 0.65

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 19/20 0.65
ADRB1 P08588 17/20 0.62
ADRB3 P13945 10/20 0.62
CHRM2 P08172 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13823217 0.92 ADRB2 (0.65) ADRB2ADRB1ADRB3CHRM2
SCHEMBL2747808 0.91 ADRB2 (0.68) ADRB2ADRB1ADRB3CHRM2
SCHEMBL13823199 0.91 ADRB2 (0.61) ADRB2ADRB1
SCHEMBL2747707 0.86 ADRB2 (0.68) ADRB2ADRB1ADRB3CHRM2
SCHEMBL2749011 0.85 ADRB2 (0.68) ADRB2ADRB1ADRB3CHRM2
SCHEMBL13823392 0.83 ADRB2 (0.60) ADRB2ADRB1ADRB3
SCHEMBL13823394 0.83 ADRB2 (0.61) ADRB2ADRB1ADRB3
SCHEMBL2747176 0.82 ADRB2 (0.67) ADRB2ADRB1ADRB3CHRM2
SCHEMBL2746764 0.82 ADRB2 (0.64) ADRB2ADRB1
SCHEMBL13823368 0.80 ADRB2 (0.69) ADRB2ADRB1ADRB3CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009068177-A1 DERIVATIVES OF 4-(2-AMINO-1 -HYDROXYETHYL)PHENOL AS AGONISTS OF THE β2 ADRENERGIC RECEPTOR ALMIRALL, S.A. (ES) 2009-06-04 WO disclosed