Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 20/20 | 1.00 |
| ▸ | DRD3 | P35462 | 20/20 | 1.00 |
| ▸ | DRD2 | P14416 | 19/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13584353 | 1.00 | HTR2A (1.00) | HTR2ADRD3DRD2 | |
| SCHEMBL13584343 | 1.00 | HTR2A (1.00) | HTR2ADRD3DRD2 | |
| SCHEMBL13583787 | 0.84 | HTR2A (1.00) | HTR2ADRD3DRD2 | |
| SCHEMBL13583786 | 0.84 | HTR2A (1.00) | HTR2ADRD3DRD2 | |
| SCHEMBL13584391 | 0.84 | DRD2 (1.00) | HTR2ADRD3DRD2 | |
| SCHEMBL13584390 | 0.84 | DRD2 (1.00) | HTR2ADRD3DRD2 | |
| SCHEMBL13584145 | 0.83 | DRD2 (1.00) | HTR2ADRD3DRD2 | |
| SCHEMBL13584142 | 0.83 | DRD2 (1.00) | HTR2ADRD3DRD2 | |
| SCHEMBL13583350 | 0.83 | HTR2A (1.00) | HTR2ADRD3DRD2 | |
| SCHEMBL13584397 | 0.83 | HTR2A (1.00) | HTR2ADRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921397-B2 | Benzofurane-piperidine compounds | HOFFMANN-LA ROCHE INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-8921397-B2 | Benzofurane-piperidine compounds | HOFFMANN-LA ROCHE INC. (US) | 2014-12-30 | — | — | US | disclosed |
| WO-2012150231-A1 | NOVEL BENZOFURANE-PIPERIDINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-11-08 | — | — | WO | disclosed |