Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | FABP7 | O15540 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13726779 | 0.94 | TDP1 (0.46) | SCN1ASCN2ASCN3ATDP1KMT2A | |
| SCHEMBL13725991 | 0.82 | FGFR1 (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13725810 | 0.81 | CACNA1D (0.44) | ALDH1A1SMN1; SMN2KDM4EGAANPC1 | |
| SCHEMBL13725930 | 0.81 | TSHR (0.45) | SCN1ASCN2ASCN3ATDP1KMT2A | |
| SCHEMBL13725656 | 0.79 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13726270 | 0.78 | PDCD1 (0.47) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13726216 | 0.78 | GRM6 (0.38) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL17117549 | 0.78 | SCN1A (0.40) | SCN1ASCN2ASCN3AKMT2AMEN1 | |
| SCHEMBL13726366 | 0.77 | TDP1 (0.45) | TDP1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13725914 | 0.77 | LMNA (0.44) | TDP1KMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160362535-A1 | 5H-FURAN-2-ONE DERIVATIVES STABILIZATION OF ORGANIC MATERIAL | BASF SCHWEIZ AG (CH) | 2016-12-15 | — | — | US | disclosed |
| US-20160362535-A1 | 5H-FURAN-2-ONE DERIVATIVES STABILIZATION OF ORGANIC MATERIAL | BASF SCHWEIZ AG (CH) | 2016-12-15 | — | — | US | disclosed |
| US-9458380-B2 | 5H-furan-2-one derivatives for stabilization of organic material | BASF SE (DE) | 2016-10-04 | — | — | US | disclosed |
| US-9458380-B2 | 5H-furan-2-one derivatives for stabilization of organic material | BASF SE (DE) | 2016-10-04 | — | — | US | disclosed |
| EP-2705082-B1 | 5H-FURAN-2-ONE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIAL | BASF SE (DE) | 2015-09-23 | — | — | EP | disclosed |
| US-20140058021-A1 | 5H-Furan-2-one Derivatives for Stabilization of Organic Material | BASF SE (DE) | 2014-02-27 | — | — | US | disclosed |
| US-20140058021-A1 | 5H-Furan-2-one Derivatives for Stabilization of Organic Material | BASF SE (DE) | 2014-02-27 | — | — | US | disclosed |
| WO-2012150527-A1 | 5H-FURAN-2-ONE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIAL | BASF SE (DE) | 2012-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160362535-A1 | 5H-FURAN-2-ONE DERIVATIVES STABILIZATION OF ORGANIC MATERIAL | C5, C9, CBR1 | SCN1A 892/4885SCN2A 617/4885SCN3A 1735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.